Would you rather collect a top star with thousands of cards or a semi-star with hundreds or cards?
I am like many collectors and I have multiple PCs with both large catalog and small catalog.
Ken Griffey Jr's catalog is huge. According to TCDB, he has 18,042 cards. This isn't counting Broder cards and some of the other unlicensed cards, so probably closer to 18,500 cards. While Jay Buhner is listed on TCDB as having 1,447 cards.
I like the idea of chasing both types of collections, sure I will probably get closer to completing Jay Buhner's entire list (not counting #1/1 type cards) then I ever will with Griffey's cards but that is part of the chase. I will always be on the watch for something new.