Since 2008 a handful of cards have been sold, usually for well below the $2,500/box price. Currently there are 2 auctions from an Australian dealer; they are both set with a BIN price set at $1237 AUD ($1276 USD).
Fast forward 4 years and we see Leaf scheduled to release the 2012 Leaf Oval Office Cut Signature set. They will once again be 1 card/box pack out but there will be slight differences. There will be a max of 275 boxes but because this is a product that will be printed based on the number of orders there may actually be less than the announced 275 boxes. Each card will be numbered to #/5 or less, another difference compared to the original 1/1 release. No price or release date has been announced but I would think the $2500/box will probably return.
This set will include single cuts of the 43 US Presidents along with dual cuts of multiple US Presidents, US Presidents/Vice Presidents, US Presidents/President's wives and a couple cards that include US Presidents and foreign leaders like FDR/Hitler, JFK/Castro, Reagan/Gorbachev and even a Ulysses S Grant/Robert E Lee.
I do want to note that on the sales sheet it states: "Cut Signatures are examples only, actual card styles may differ after production"